Barbiturates were developed at the end of the 19th century and were marketed as sedative drugs to treat ailments ranging from insomnia to seizures. When introduced to the market, they shot to popularity for their ability to alleviate these conditions, but they hid a dark secret. Little did scientists know at the time, but these were some of the most addictive and dangerous drugs ever created. 

Barbiturates fall under a class of drugs known as central nervous system (CNS) depressants that assist in slowing down an overactive nervous system, which is typically the cause behind the ailments discussed above. They are considered a controlled substance by the United States Drug Enforcement Administration (DEA) and have fallen out of popularity in recent times. Nembutal is a Schedule II substance, meaning it contains medicinal uses but will likely cause physical dependence and be abused. 

As barbiturates fell out of doctors’ good wishes, they were replaced with still addictive but less deadly benzodiazepines. However, despite their reluctance to prescribe and strict regulations by the government, drugs like Nembutal still fall into the hands of users on the street, leading to serious and sometimes deadly withdrawal symptoms. 

Withdrawal Syndrome

Withdrawal syndrome, also known as discontinuation syndrome, happens when an individual has developed a physical dependence on specific drugs or alcohol. Physical dependence will lead to the development of both tolerance to Nembutal and withdrawal syndrome. 

Tolerance is characterized by a person who no longer feels the effects of a particular dosage of Nembutal when they’ve been using it over a prolonged period. Their system acclimates to the drug, and they’ll need to start using more Nembutal to feel the effects they once felt at a lower dose. Those who abuse the drug often do so for its mind-altering effects. A tolerance eventually becomes a nuisance because they’ll have to take higher doses to feel the same impact. When it comes to Nembutal, this can lead to dangerous and sometimes fatal overdoses. Barbiturates are extremely dangerous drugs to abuse. 

When tolerance develops, the person’s system will adjust itself to the presence of Nembutal in its tissues. It alters specific aspects of its functioning, including the production of neurotransmitters and hormones to compensate for the drug in its system. As they continue using higher doses, their system will adjust to a point where it no longer functions normally without the drug in its tissues. When a person cuts down the dosage or stops abruptly, the system gets thrown out of whack, leading to a number of emotional and physical side effects. Most of which are highly unpleasant. 

When a person develops both tolerance and withdrawal symptoms, they become physically dependent on Nembutal and will only function normally when the drug is in their system. Although the development of physical dependence can be a sign of addiction, it doesn’t always indicate a substance use disorder (SUD). For example, a person with epilepsy who uses Nembutal as prescribed may develop a tolerance but would not receive a substance use disorder diagnosis. 

A substance use disorder occurs when someone uses drugs for nonmedical reasons and has issues controlling their use. In addition, they’ll continue using despite experiencing adverse consequences as a result of their use. 

What are Nembutal Withdrawal Symptoms?

Those who establish a dependency on Nembutal will experience it rapidly. Unfortunately, this may lead to dangerous outcomes. Signs of Nembutal abuse are similar to alcohol intoxication that includes slurred speech and stumbling. 

Abrupt cessation of Nembutal will lead to withdrawal symptoms that will vary from mild to severe. These symptoms could start in as little as nine to 12 hours after your last dose, dependent on several factors. 

The most common symptoms of Nembutal withdrawal include the following:

  • Dizziness
  • Anxiety
  • Tremors
  • Muscle twitching
  • Convulsions
  • Feeling weak or fatigued
  • Confusion
  • Vomiting
  • Insomnia
  • Low blood pressure
  • Upset stomach
  • Seizures
  • Delirium 

Stages of the Nembutal Withdrawal Timeline

As a barbiturate, Nembutal will follow a timeline you might expect from a drug in this category. The most common factors that influence the following timeline include:

  • Age
  • Tapering schedule
  • The dose you’ve been accustomed to taking
  • Dietary habits
  • Overall health condition
  • Frequency of use
  • Duration of Nembutal use


Although the symptoms and timeline will affect everyone differently, the following is a generalized Nembutal timeline of withdrawal symptoms:

  • Days 1-3: As was mentioned above, the most common timing symptoms will appear is around nine to 12 hours after the last dose. The onset of Nembutal withdrawal symptoms will include anxiety, sweating, insomnia, and body weakness. To avoid delirium or seizures, you should taper off Nembutal slowly to avoid shocking your body. 
  • Days 3-4: At this stage, the person going through Nembutal withdrawal will reach the peak of their symptoms. As previously mentioned, the intensity of their peak will be determined by the factors above. The most common symptoms are severe insomnia, anxiety, and in some cases, delirium. You should consider medical detox at this stage to avoid potential fatal outcomes. 
  • Days 5-7: At this stage, physical symptoms will start decreasing, but the individual will still experience cravings and depression.
  • Week 2 and beyond: At this stage, acute withdrawal symptoms should dissipate. However, psychological symptoms could persist. Those in recovery report feeling cravings, exhaustion, and an inability to sleep. Most others report by weeks three or four that they are symptom-free. 

The Risk of Overdose

As with any barbiturate drug, the risk of overdose is high, especially when a person stops using Nembutal for a period and starts using again. Relapsing on Nembutal can be especially dangerous because when someone detoxes from the drug, their body’s tolerance will be significantly lower. Although this is the case with any drug, barbiturates have a much smaller margin of error when it comes to dosing

Should I Detox?

Since barbiturates like Nembutal carry such significant withdrawal symptoms, stopping without help can be dangerous. Seeking the proper support and checking yourself into a controlled environment will ensure your safety and help alleviate some of the worst symptoms you might experience during these challenging moments. During detox, you could end up staying anywhere from five to seven days, depending on the severity of your addiction. 

The short answer is yes; you should absolutely detox if you’re addicted to Nembutal. You’ll have 24-hour access to medical professionals who can monitor your status and administer the proper medications to ensure your comfort during this stage. In detox, you’ll work alongside addiction specialists to create a recovery plan, which could mean long-term inpatient treatment moving forward. Each case is unique and will be treated as such. 

What is the Next Treatment Step?

Although detox is one of the most challenging steps in the recovery process, it’s not enough to achieve sobriety in the long-term. Detox helps purge the drugs from your body, but it doesn’t do anything to address the underlying causes that pushed you to abuse Nembutal in the first place. When detox is completed, the individual must continue in an inpatient or outpatient facility to receive ongoing care. By doing so, they can work on the emotional and mental health issues that contributed to their addiction. 

Nembutal addiction treatment will vary from one person to another based on their level of dependency, which will be established in detox when meeting with clinicians to determine a roadmap. If they decide that inpatient treatment is the best course of action, the individual will reside on-site for a period of up to 90 days, which the National Institute on Drug Abuse (NIDA) recommends as the most effective means of treatment

When living on-site, the individual will be around counselors and physicians around-the-clock in a supportive atmosphere where a person can focus on recovery without distraction. This type of treatment is recommended for those who are heavily addicted to Nembutal and have a history of relapsing. 

Outpatient treatment is when a person attends addiction therapies and is active in their recovery but can go home once they are complete. This is an ideal option for a person using treatment as a barrier because of school, work, or other pressing obligations. It could be three to seven therapy sessions a week but will change the person’s life. This treatment is better for those who are mildly addicted and don’t have a history of relapse. For example, someone who became dependent on the drug when using it as prescribed might be better off in outpatient treatment.

Tap to GET HELP NOW: (888) 783-3291